Estimation of parameters in DNA mixture analysis
نویسندگان
چکیده
منابع مشابه
Numerical analysis of EM estimation of mixture model parameters
Optimisation of distribution parameters is a very common problem. There are many sorts of distributions which can be used to model environment processes, biological functions or graphical data. However, it is common that parameters of those distribution may be, partially or completely unknown. Mixture models composed of a few distributions are easier to solve. In such a case simple estimation m...
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DNA abundance provides important information about cell physiology and proliferation activity. In a typical in vitro cellular assay, the distribution of the DNA content within a sample is comprised of cell debris, G0/G1-, S-, and G2/M-phase cells. In some circumstances, there may be a collection of cells that contain more than two copies of DNA. The primary focus of DNA content analysis is to d...
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ژورنال
عنوان ژورنال: Journal of Applied Statistics
سال: 2013
ISSN: 0266-4763,1360-0532
DOI: 10.1080/02664763.2013.817549